ARAP1 Polyclonal Antibody, 100ul Immunology Probable anchoring protein which tethers

Probable anchoring protein which tethers the nucleus to the cytoskeleton by binding PLEC which can associate with the intermediate filament system

The presence of this protein in blood and urine is an early biomarker of acute kidney injury

The beta subunit is the same in both the muscle and hepatic isoforms

Multiple alternatively spliced transcript variants have been described for PARD3

ARAP1 Polyclonal Antibody, 100ul Immunology Probable anchoring protein which tethersThe protein encoded by this gene contains SAM, ARF GAP, RHO GAP, ankyrin repeat, RAS associating, and pleckstrin homology (PH) domains. In vitro, this protein displays RHO GAP and phosphatidylinositol (3,4,5) trisphosphate (PIP3) dependent ARF GAP activity. The encoded protein associates with the Golgi, and the ARF GAP activity mediates changes in the Golgi and the formation of filopodia. It is thought to regulate the cell specific trafficking of a