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p53 (Acetyl Lys372) Polyclonal Antibody, 50ul Protein Post-translational Modification PTM:The N-terminus is blocked

SKU: 44822225262

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p53 (Acetyl Lys372) Polyclonal Antibody, 50ul Protein Post-translational Modification PTM:The N-terminus is blockedTP53 encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. Tumor protein p53 responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in TP53 are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni syndrome. Alternative

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Description

PTM:The N-terminus is blocked

which is characterized by a distinctive mid-hindbrain and cerebellar malformation

contains over 3000 genes and comprises nearly 8% of the human genome

These two variants encode distinct isoforms which differ in activity and regulation

p53 (Acetyl Lys372) Polyclonal Antibody, 50ul Protein Post-translational Modification PTM:The N-terminus is blockedTP53 encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. Tumor protein p53 responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in TP53 are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni syndrome. Alternative

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