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Flt3-L Polyclonal Antibody, 50ul[BT-AP03284] Antibody Humanization Like its somatic cell counterpart

SKU: 45831330598

4.6
USD162.00 USD212.00

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Flt3-L Polyclonal Antibody, 50ul[BT-AP03284] Antibody Humanization Like its somatic cell counterpartDendritic cells (DCs) provide the key link between innate and adaptive immunity by recognizing pathogens and priming pathogen specific immune responses. FLT3LG controls the development of DCs and is particularly important for plasmacytoid DCs and CD8 (see MIM 186910) positive classical DCs and their CD103 (ITGAE; MIM 604682) positive tissue counterparts (summary by Sathaliyawala et al. 2010 [PubMed: 20933441]).

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Description

Like its somatic cell counterpart

|PTM:Phosphorylation by PKB/AKT1 inhibits transcriptional activity and is responsible for cytoplasmic localization

Multiple transcript variants encoding different isoforms have been found for CALM1

Alternative splicing has been observed in this gene

Flt3-L Polyclonal Antibody, 50ul[BT-AP03284] Antibody Humanization Like its somatic cell counterpartDendritic cells (DCs) provide the key link between innate and adaptive immunity by recognizing pathogens and priming pathogen specific immune responses. FLT3LG controls the development of DCs and is particularly important for plasmacytoid DCs and CD8 (see MIM 186910) positive classical DCs and their CD103 (ITGAE; MIM 604682) positive tissue counterparts (summary by Sathaliyawala et al. 2010 [PubMed: 20933441]).

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