SFRP1 Polyclonal Antibody, 100ul Vessels Overactivation of type I interferon

Overactivation of type I interferon secretion is linked to autoimmune diseases

It has been suggested that defects in the human gene result in pipecolic acidemia

PDZ 5 mediates the C-terminal binding of GRIA2 and GRIA3

The protein also interacts with proteins that function as linkers between integral membrane and cytoskeletal proteins

SFRP1 Polyclonal Antibody, 100ul Vessels Overactivation of type I interferonThis gene encodes a member of the SFRP family that contains a cysteine rich domain homologous to the putative Wnt binding site of Frizzled proteins. Members of this family act as soluble modulators of Wnt signaling; epigenetic silencing of SFRP genes leads to deregulated activation of the Wnt pathway which is associated with cancer. This gene may also be involved in determining the polarity of photoreceptor cells in the retina.