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basic transcriptional factor and also as a bifunctional transcriptional regulator

and directly interacts with the tumor suppressor p53 to reduce p53 transcriptional activity by reducing p53 protein level in the absence of DNA damage

The Aly/REF export factor encoded by ALYREF is a heat stable

GMDS Polyclonal Antibody, 50ul Sealing Film Say goodbye to contamination worriesGDP mannose 4,6 dehydratase (GMD; EC 4. 2. 1. 47) catalyzes the conversion of GDP mannose to GDP 4 keto 6 deoxymannose, the first step in the synthesis of GDP fucose from GDP mannose, using NADP+ as a cofactor. The second and third steps of the pathway are catalyzed by a single enzyme, GDP keto 6 deoxymannose 3,5 epimerase, 4 reductase, designated FX in humans (MIM 137020).