CHD5 Polyclonal Antibody, 100ul Cell Culture Flasks Genetic variation at this locus

Genetic variation at this locus has been associated with a range of behavioral phenotypes

the protein mutated in Huntington disease (HD)

known to regulate formation of actin filaments

The use of alternative translation start sites results in isoforms with longer or shorter N-termini which may differ in their subcellular localizations

CHD5 Polyclonal Antibody, 100ul Cell Culture Flasks Genetic variation at this locusThis gene encodes a member of the chromodomain helicase DNA binding protein family. Members of this family are characterized by a chromodomain, a helicase ATP binding domain and an additional functional domain. This gene encodes a neuron specific protein that may function in chromatin remodeling and gene transcription. This gene is a potential tumor suppressor gene that may play a role in the development of neuroblastoma.