IGF2-BP2 Polyclonal Antibody, 100ul Antibodies Mutations in this gene cause

Mutations in this gene cause hyperlipoproteinemia type IB

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which implicates its role in cancer invasion

The first two N-terminal amino acids can be cleaved from human CCL4 by CD26/DPPIV

IGF2-BP2 Polyclonal Antibody, 100ul Antibodies Mutations in this gene causeIGF2BP2 encodes a member of the IGF II mRNA binding protein (IMP) family. The insulin like growth factor 2 mRNA binding protein 2 encoded by this gene contains four KH domains and two RRM domains. It functions by binding to the 5' UTR of the insulin like growth factor 2 (IGF2) mRNA and regulating IGF2 translation. Alternative promoter usage and alternate splicing result in multiple variants encoding different isoforms.