Keap1 Polyclonal Antibody, 50ul Cell Screening and Imaging Mutations in this gene have

Mutations in this gene have been associated with dyschromatosis symmetrica hereditaria

May prevent inappropriate targeting of non-secretory polypeptides to the endoplasmic reticulum (ER)

and B cells

The transcription of this gene is activated by PPAR-gamma| and the resulting protein product plays a role in endothelial cell migration

Keap1 Polyclonal Antibody, 50ul Cell Screening and Imaging Mutations in this gene haveKEAP1 encodes a protein containing KELCH 1 like domains, as well as a BTB POZ domain. Kelch like ECH associated protein 1 interacts with NF E2 related factor 2 in a redox sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF E2 related factor 2 to the nucleus. This interaction results in the expression of the catalytic subunit of gamma glutamylcysteine synthetase. Two alternatively spliced