MPO Polyclonal Antibody, 100ul Molecular Biologyn The protein functions as a

The protein functions as a guanine nucleotide exchange factor for the small GTPase RAB5

the C-terminal kinase domain binds to its own N-terminal region

The protein encoded by this gene binds to the fibronectin type III domains of ITGB4 and may help link ITGB4 to the intermediate filament cytoskeleton

The protein functions in cap-independent translation of ornithine decarboxylase mRNA

MPO Polyclonal Antibody, 100ul Molecular Biologyn The protein functions as aMyeloperoxidase (MPO) is a heme protein synthesized during myeloid differentiation that constitutes the major component of neutrophil azurophilic granules. Produced as a single chain precursor, myeloperoxidase is subsequently cleaved into a light and heavy chain. The mature myeloperoxidase is a tetramer composed of 2 light chains and 2 heavy chains. This enzyme produces hypohalous acids central to the microbicidal activity of neutrophils.