Rb Polyclonal Antibody, 20ul[BT-AP07693] Pathway and Network Analysis As part of a histone

As part of a histone H3-specific methyltransferase complex may mediate ligand-dependent transcriptional activation by nuclear hormone receptors

There are two isoforms of PRPF38A that are produced as a result of alternative splicing events

HNRP proteins have also been identified outside of the nucleoplasm

In several BTB/POZ containing proteins

Rb Polyclonal Antibody, 20ul[BT-AP07693] Pathway and Network Analysis As part of a histoneThe protein encoded by RB1 (RB transcriptional corepressor 1) is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in RB1 are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.