Dkk-1 Polyclonal Antibody, 50ul Funnels and an unprocessed pseudogene has

and an unprocessed pseudogene has been found on chromosome 10

by proteolytic processing

and in the study of protein-protein interactions

This gene is a member of the inositol polyphosphate-5-phosphatase (INPP5) family and encodes a protein with an N-terminal SH2 domain

Dkk-1 Polyclonal Antibody, 50ul Funnels and an unprocessed pseudogene hasDKK1 encodes dickkopf WNT signaling pathway inhibitor 1 that is a member of the dickkopf family. It is a secreted protein with two cysteine rich regions and is involved in embryonic development through its inhibition of the WNT signaling pathway. Elevated levels of DKK1 in bone marrow plasma and peripheral blood is associated with the presence of osteolytic bone lesions in patients with multiple myeloma.