BRMS-1 Polyclonal Antibody, 20ul[BT-AP00979] Cell Screening and Imaging Studies in mice have shown

Studies in mice have shown that this particular histone is required for embryonic development and indicate that lack of functional histone H2A leads to embryonic lethality

Alternatively spliced transcript variants encoding multiple isoforms have been observed for ABCB7

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BRMS-1 Polyclonal Antibody, 20ul[BT-AP00979] Cell Screening and Imaging Studies in mice have shownBRMS1 reduces the metastatic potential, but not the tumorogenicity, of human breast cancer and melanoma cell lines. Breast cancer metastasis suppressor 1 encoded by this gene localizes primarily to the nucleus and is a component of the mSin3a family of histone deacetylase complexes (HDAC). The protein contains two coiled coil motifs and several imperfect leucine zipper motifs. Alternative splicing results in two transcript variants encoding different