FRS3 Polyclonal Antibody, 100ul Bottles Mutations in this gene have

Mutations in this gene have been observed in patients with adrenoleukodystrophy| a severe

and also ovarian hyperstimulation syndrome

It is located within a homozygously deleted region of a metastatic prostate cancer

This gene encodes a transmembrane protein with two extracellular Kunitz domains that inhibits a variety of serine proteases

FRS3 Polyclonal Antibody, 100ul Bottles Mutations in this gene haveFRS3 encodes a substrate for the fibroblast growth factor receptor. Fibroblast growth factor receptor substrate 3 is found in the peripheral plasma membrane and links fibroblast growth factor receptor stimulation to activators of Ras. Fibroblast growth factor receptor substrate 3 down regulates extracellular regulated kinase 2 through direct binding.