SHIP-2 Polyclonal Antibody, 100ul Protein Post-translational Modification Alternative splicing results in multiple

Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing to generate mature polypeptides

three epidermal growth factor (EGF)-like domains and three fibronectin type III repeats

BinCARD plays a role in inhibiting the effects of Bcl10-induced activation of NFκB possibly by inhibiting the phosphorylation of Bcl10 in a CARD-dependent manner

Binds differentially to the SH3 domains of certain proteins of signal transduction pathways

SHIP-2 Polyclonal Antibody, 100ul Protein Post-translational Modification Alternative splicing results in multiplePhosphatidylinositol 3,4,5 trisphosphate 5 phosphatase 2 encoded by INPPL1 is an SH2 containing 5' inositol phosphatase that is involved in the regulation of insulin function. The encoded protein also plays a role in the regulation of epidermal growth factor receptor turnover and actin remodelling. Additionally, this gene supports metastatic growth in breast cancer and is a valuable biomarker for breast cancer.