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Cadherin-23 Polyclonal Antibody, 50ul Custom DNA Oligos This Mediator component binds with

SKU: 56854836760

4.3
USD162.00 USD212.00

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Cadherin-23 Polyclonal Antibody, 50ul Custom DNA Oligos This Mediator component binds withCDH23 (cadherin related 23) is a member of the cadherin superfamily, whose genes encode calcium dependent cell cell adhesion glycoproteins. The encoded protein is thought to be involved in stereocilia organization and hair bundle formation. CDH23 is located in a region containing the human deafness loci DFNB12 and USH1D. Usher syndrome 1D and nonsyndromic autosomal recessive deafness DFNB12 are caused by allelic mutations of this cadherin like gene.

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Description

This Mediator component binds with a CDK8 subcomplex which contains the protein encoded by the gene

The protein also interacts with activated Smad family member 2 (Smad2) and its nuclear partner forkhead box H1 (also known as FAST-1)

induction:By MYC overexpression in a concentration dependent manner in neuroblastoma cell line

including the trachea

Cadherin-23 Polyclonal Antibody, 50ul Custom DNA Oligos This Mediator component binds withCDH23 (cadherin related 23) is a member of the cadherin superfamily, whose genes encode calcium dependent cell cell adhesion glycoproteins. The encoded protein is thought to be involved in stereocilia organization and hair bundle formation. CDH23 is located in a region containing the human deafness loci DFNB12 and USH1D. Usher syndrome 1D and nonsyndromic autosomal recessive deafness DFNB12 are caused by allelic mutations of this cadherin like gene.

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