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ZMAT3 Polyclonal Antibody, 100ul Custom RNA Oligos Mutations and deletions in this

SKU: 57083060387

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ZMAT3 Polyclonal Antibody, 100ul Custom RNA Oligos Mutations and deletions in thisThis gene encodes a protein containing three zinc finger domains and a nuclear localization signal. The mRNA and the protein of this gene are upregulated by wildtype p53 and overexpression of this gene inhibits tumor cell growth, suggesting that this gene may have a role in the p53 dependent growth regulatory pathway. Alternative splicing of this gene results in two transcript variants encoding two isoforms differing in only one amino acid.

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Description

Mutations and deletions in this gene are associated with benign hereditary chorea| choreoathetosis| congenital hypothyroidism| and neonatal respiratory distress| and may be associated with thyroid cancer

Together with RAB11A

and miRNA-200b is itself downregulated in glioma tissues

which is involved in large ribosomal subunit biogenesis

ZMAT3 Polyclonal Antibody, 100ul Custom RNA Oligos Mutations and deletions in thisThis gene encodes a protein containing three zinc finger domains and a nuclear localization signal. The mRNA and the protein of this gene are upregulated by wildtype p53 and overexpression of this gene inhibits tumor cell growth, suggesting that this gene may have a role in the p53 dependent growth regulatory pathway. Alternative splicing of this gene results in two transcript variants encoding two isoforms differing in only one amino acid.

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