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Ku-70 Polyclonal Antibody, 20ul[BT-AP04893] Protein Research multiprotein complexes at the dermal-epidermal

SKU: 6047929409

4.7
PLN97.20 PLN138.20

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Ku-70 Polyclonal Antibody, 20ul[BT-AP04893] Protein Research multiprotein complexes at the dermal-epidermalThe p70 p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single stranded DNA dependent ATP dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with

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Description

multiprotein complexes at the dermal-epidermal basement membrane zone that mediate adhesion of keratinocytes to the underlying membrane

Mutations in the corresponding AQP2 gene cause a rare form of diabetes known as nephrogenic diabetes insipidus

and transcript variant one includes only gene-specific exons

It plays a critical role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme and inhibits endothelial permeability

Ku-70 Polyclonal Antibody, 20ul[BT-AP04893] Protein Research multiprotein complexes at the dermal-epidermalThe p70 p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single stranded DNA dependent ATP dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with

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