Plakophilin 2 Polyclonal Antibody, 100ul Serological Pipets The alpha subunit is composed

The alpha subunit is composed of an heavy and a light chain linked by a disulfide bond

This gene encodes a member of the Nedd4 family of HECT domain E3 ubiquitin ligases

Some of these isoforms are beta subunits

It is also involved in oogenesis and in neuronal differentiation

Plakophilin 2 Polyclonal Antibody, 100ul Serological Pipets The alpha subunit is composedPKP2 encodes a member of the arm repeat (armadillo) and plakophilin gene families. Plakophilin proteins contain numerous armadillo repeats, localize to cell desmosomes and nuclei, and participate in linking cadherins to intermediate filaments in the cytoskeleton. PKP2 product may regulate the signaling activity of beta catenin. Two alternately spliced transcripts encoding two protein isoforms have been identified. A processed pseudogene with high