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CD55 Polyclonal Antibody, 100ul[BT-AP01880] Shakers whereby it binds complement C8

SKU: 62797745879

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CD55 Polyclonal Antibody, 100ul[BT-AP01880] Shakers whereby it binds complement C8The first component of complement is a calcium dependent complex of the 3 subcomponents C1q, C1r, and C1s. The serine protease subunits C1r and C1s form a Ca(2+) dependent C1s C1r C1r C1s tetramer. C1r acts by transforming the activation signal into an enzymic activity. C1r is a single chain glycoprotein which can be cleaved into an A chain and a B chain upon activation. This antibody recognizes full length C1r chain and the cleaved B chain.

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Description

whereby it binds complement C8 and/or C9 during the assembly of this complex

which is required for p53-mediated transcription activation

FAM90A9 belongs to subfamily II of the primate-specific FAM90A gene family| which originated from multiple duplications and rearrangements (Bosch et al

1987 [PubMed 2446322]

CD55 Polyclonal Antibody, 100ul[BT-AP01880] Shakers whereby it binds complement C8The first component of complement is a calcium dependent complex of the 3 subcomponents C1q, C1r, and C1s. The serine protease subunits C1r and C1s form a Ca(2+) dependent C1s C1r C1r C1s tetramer. C1r acts by transforming the activation signal into an enzymic activity. C1r is a single chain glycoprotein which can be cleaved into an A chain and a B chain upon activation. This antibody recognizes full length C1r chain and the cleaved B chain.

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