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PEN2 Rabbit Polyclonal Antibody, 100ul miRNA / siRNA Synthesis |PTM:Phosphorylation on Ser-421 and Ser-423

SKU: 64616697107

4.1
PLN123.75 PLN163.75

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PEN2 Rabbit Polyclonal Antibody, 100ul miRNA / siRNA Synthesis |PTM:Phosphorylation on Ser-421 and Ser-423Presenilins which are components of the gamma secretase protein complex are required for intramembranous processing of some type I transmembrane proteins such as the Notch proteins and the beta amyloid precursor protein. Signaling by Notch receptors mediates a wide range of developmental cell fates. Processing of the beta amyloid precursor protein generates neurotoxic amyloid beta peptides the major component of senile plaques associated with

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Description

|PTM:Phosphorylation on Ser-421 and Ser-423 promotes enzymatic activity and interactions with NuRD and SIN3 complexes

Does not affect the proliferation of cancer cells in vitro

NECTIN1 encodes nectin cell adhesion molecule 1 that plays a role in the organization of adherens junctions and tight junctions in epithelial and endothelial cells

which are binding partners to the RAB5 small GTPases

PEN2 Rabbit Polyclonal Antibody, 100ul miRNA / siRNA Synthesis |PTM:Phosphorylation on Ser-421 and Ser-423Presenilins which are components of the gamma secretase protein complex are required for intramembranous processing of some type I transmembrane proteins such as the Notch proteins and the beta amyloid precursor protein. Signaling by Notch receptors mediates a wide range of developmental cell fates. Processing of the beta amyloid precursor protein generates neurotoxic amyloid beta peptides the major component of senile plaques associated with

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