NEDD4L(Phospho-Ser342) Rabbit Polyclonal Antibody, 50ul Cytokines Two transcript variants encoding distinct

Two transcript variants encoding distinct isoforms have been described

In mitosis RCC1 is phosphorylated at Ser11

Loss of function mutations in SLC16A2 are associated with psychomotor retardation in males while females exhibit no neurological defects and more moderate thyroid-deficient phenotypes

The encoded protein may be a key regulator of blood pressure by controlling the transport of sodium and chloride ions

NEDD4L(Phospho-Ser342) Rabbit Polyclonal Antibody, 50ul Cytokines Two transcript variants encoding distinctThis gene encodes a member of the Nedd4 family of HECT domain E3 ubiquitin ligases. HECT domain E3 ubiquitin ligases transfer ubiquitin from E2 ubiquitin conjugating enzymes to protein substrates thus targeting specific proteins for lysosomal degradation. The encoded protein mediates the ubiquitination of multiple target substrates and plays a critical role in epithelial sodium transport by regulating the cell surface expression of the epithelial