Tyrosine Hydroxylase Polyclonal Antibody, 50ul Filtration RUNX3 encodes a member of

RUNX3 encodes a member of the runt domain-containing family of transcription factors

alternative products:Additional isoforms exist

also gamma I has an allelic variant gamma II

developmental stage:Expression in neutrophils occurs in the late terminal differentiation phase

Tyrosine Hydroxylase Polyclonal Antibody, 50ul Filtration RUNX3 encodes a member ofThe protein encoded by this gene is involved in the conversion of tyrosine to dopamine. It is the rate limiting enzyme in the synthesis of catecholamines, hence plays a key role in the physiology of adrenergic neurons. Mutations in this gene have been associated with autosomal recessive Segawa syndrome. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.