Vav1 Polyclonal Antibody, 50ul[BT-AP09488] Pathway and Network Analysis Mutation in this gene was

Mutation in this gene was also observed in individuals with metacarpal 4-5 fusion

Mutations in EPHA2 are the cause of certain genetically-related cataract disorders

May be required for both optimal rDNA transcription and small subunit (SSU) pre-rRNA processing at sites A

They form 14-15 kDa proteins and are thought to participate in the uptake| intracellular metabolism and/or transport of long-chain fatty acids

Vav1 Polyclonal Antibody, 50ul[BT-AP09488] Pathway and Network Analysis Mutation in this gene wasVAV1 is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. The Proto oncogene vav is important in hematopoiesis, playing a role in T cell and B cell development and activation. The encoded protein has been identified as the specific binding partner of Nef proteins from HIV 1.