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YMEL1 Rabbit Polyclonal Antibody, 100ul Cryopreservation It is a multi-pass membrane

SKU: 66523083778

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YMEL1 Rabbit Polyclonal Antibody, 100ul Cryopreservation It is a multi-pass membraneThe protein encoded by this gene is the human ortholog of yeast mitochondrial AAA metalloprotease Yme1p. It is localized in the mitochondria and can functionally complement a yme1 disruptant yeast strain. It is proposed that this gene plays a role in mitochondrial protein metabolism and could be involved in mitochondrial pathologies. Three transcript variants encoding different isoforms have been found for this gene.

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Description

It is a multi-pass membrane protein which contains a ClC domain and two additional C-terminal CBS (cystathionine beta-synthase) domains

member 4) is a member of the SWI/SNF family of proteins and is similar to the brahma protein of Drosophila

Defects in SERPINE1 are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency)

This protein is found associated with endosomal membranes

YMEL1 Rabbit Polyclonal Antibody, 100ul Cryopreservation It is a multi-pass membraneThe protein encoded by this gene is the human ortholog of yeast mitochondrial AAA metalloprotease Yme1p. It is localized in the mitochondria and can functionally complement a yme1 disruptant yeast strain. It is proposed that this gene plays a role in mitochondrial protein metabolism and could be involved in mitochondrial pathologies. Three transcript variants encoding different isoforms have been found for this gene.

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