Rat Nephrin, NPHN ELISA Kit, 96T Yeast Expression Northern blotting studies have shown

Northern blotting studies have shown that the gene expression is predominantly found in morphologically differentiated neurologic cells

cleaves SPHK2 which is released from cells and remains enzymatically active extracellularly

Component of RNA polymerase I which synthesizes ribosomal RNA precursors

It also plays a role in nuclear pre-mRNA retention and transcriptional repression

Rat Nephrin, NPHN ELISA Kit, 96T Yeast Expression Northern blotting studies have shownSeems to play a role in the development or function of the kidney glomerular filtration barrier. Regulates glomerular vascular permeability. May anchor the podocyte slit diaphragm to the actin cytoskeleton. Plays a role in skeletal muscle formation through regulation of myoblast fusion.