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CD6 Polyclonal Antibody, 100ul[BT-AP01961] Culture Media has a putative extracellular domain

SKU: 67996710180

4.2
PLN123.75 PLN171.75

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CD6 Polyclonal Antibody, 100ul[BT-AP01961] Culture Media has a putative extracellular domainKLKB1 encodes a glycoprotein that participates in the surface dependent activation of blood coagulation, fibrinolysis, kinin generation and inflammation. The encoded preproprotein present in plasma as a non covalent complex with high molecular weight kininogen undergoes proteolytic processing mediated by activated coagulation factor XII to generate a disulfide linked, heterodimeric serine protease comprised of heavy and light chains. Certain mutations

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Description

has a putative extracellular domain with five immunoglobulin (Ig)-like loops and three fibronectin (Fn) type III motifs

This gene encodes a ubiquitin specific processing protease that was first identified as a substrate of the VHL (von Hippel-Lindau disease) protein E3 ubiquitin ligase complex

with the last serine residue replaced by alanine

Transcripts initiating from the downstream promoter encode beta isoforms

CD6 Polyclonal Antibody, 100ul[BT-AP01961] Culture Media has a putative extracellular domainKLKB1 encodes a glycoprotein that participates in the surface dependent activation of blood coagulation, fibrinolysis, kinin generation and inflammation. The encoded preproprotein present in plasma as a non covalent complex with high molecular weight kininogen undergoes proteolytic processing mediated by activated coagulation factor XII to generate a disulfide linked, heterodimeric serine protease comprised of heavy and light chains. Certain mutations

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