CETN2 Rabbit Polyclonal Antibody, 50ul Peptide Synthesis The encoded transmembrane protein is

The encoded transmembrane protein is characterized by a type II membrane orientation (has an extracellular C terminus) and the presence of a C-type lectin domain

which is an inhibitory subunit

Catalytic activity:ATP + thymidine = ADP + thymidine 5'-phosphate

TOP2A encoding this enzyme functions as the target for several anticancer agents and a variety of mutations in this gene have been associated with the development of drug resistance

CETN2 Rabbit Polyclonal Antibody, 50ul Peptide Synthesis The encoded transmembrane protein isCaltractin belongs to a family of calcium binding proteins and is a structural component of the centrosome. The high level of conservation from algae to humans and its association with the centrosome suggested that caltractin plays a fundamental role in the structure and function of the microtubule organizing center, possibly required for the proper duplication and segregation of the centrosome.