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c-Fos Monoclonal Antibody(6A3), 50ul Lentiviral Packaging VGF (VGF nerve growth factor

SKU: 68304550046

4.3
USD185.00 USD227.00

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c-Fos Monoclonal Antibody(6A3), 50ul Lentiviral Packaging VGF (VGF nerve growth factorThe Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP 1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. In some cases, expression of the FOS gene has also been associated with apoptotic cell death.

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Description

VGF (VGF nerve growth factor inducible) is specifically expressed in a subpopulation of neuroendocrine cells

Members of this Type I transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats| and an intracellular domain consisting of multiple different domain types

It functions as a major molecular target for the immunosuppressive drugs such as cyclosporin A

which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors

c-Fos Monoclonal Antibody(6A3), 50ul Lentiviral Packaging VGF (VGF nerve growth factorThe Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP 1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. In some cases, expression of the FOS gene has also been associated with apoptotic cell death.

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