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PCSK9 Rabbit Polyclonal Antibody, 50ul[BT-AP11847] Bottle-Top Dispenser while CUL-2 associates with the

SKU: 68518268645

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PCSK9 Rabbit Polyclonal Antibody, 50ul[BT-AP11847] Bottle-Top Dispenser while CUL-2 associates with theProprotein convertase subtilisin kexin type 9 (PCSK9) is an enzyme encoded by the PCSK9 gene in humans on chromosome 1. It is the 9th member of the proprotein convertase family of proteins that activate other proteins. Similar genes (orthologs) are found across many species. As with many proteins, PCSK9 is inactive when first synthesized, because a section of peptide chains blocks their activity; proprotein convertases remove that section to activate

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Description

while CUL-2 associates with the tumor suppressing protein VHL and elongin B to form VBC complexes

Mutations in this gene are associated with methylmalonic aciduria

It promotes adhesion of endothelial cells through interaction of integrins and the RGD motif

Alternatively spliced transcript variants encoding distinct isoforms have been reported

PCSK9 Rabbit Polyclonal Antibody, 50ul[BT-AP11847] Bottle-Top Dispenser while CUL-2 associates with theProprotein convertase subtilisin kexin type 9 (PCSK9) is an enzyme encoded by the PCSK9 gene in humans on chromosome 1. It is the 9th member of the proprotein convertase family of proteins that activate other proteins. Similar genes (orthologs) are found across many species. As with many proteins, PCSK9 is inactive when first synthesized, because a section of peptide chains blocks their activity; proprotein convertases remove that section to activate

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