SMAD7 Polyclonal Antibody, 100ul Diagnostic Probes & Oligos Defects in this gene are

Defects in this gene are a cause of zonular pulverulent cataract type 3 (CZP3)

CALD1 encodes a calmodulin- and actin-binding protein (caldesmon 1) that plays an essential role in the regulation of smooth muscle and nonmuscle contraction

Mannose receptor C type 2 plays a role in extracellular matrix remodeling by mediating the internalization and lysosomal degradation of collagen ligands

This protein exhibits mitogenic activity for keratinizing epidermal cells

SMAD7 Polyclonal Antibody, 100ul Diagnostic Probes & Oligos Defects in this gene areThe protein encoded by this gene is a nuclear protein that binds the E3 ubiquitin ligase SMURF2. Upon binding, this complex translocates to the cytoplasm, where it interacts with TGF beta receptor type 1 (TGFBR1), leading to the degradation of both the encoded protein and TGFBR1. Expression of this gene is induced by TGFBR1. Variations in this gene are a cause of susceptibility to colorectal cancer type 3 (CRCS3). Several transcript variants encoding