RNF6 Polyclonal Antibody, 100ul Centrifugal Filter Differential expression of this gene

Differential expression of this gene has been observed in different types of malignancies

present throughout the cell cycle

The protein encoded by this gene is a G protein-coupled receptor which activates a phosphatidylinositol-calcium second messenger system

and CDC42 (MIM 116952)

RNF6 Polyclonal Antibody, 100ul Centrifugal Filter Differential expression of this geneThe protein encoded by this gene contains a RING H2 finger motif. Deletions and mutations in this gene were detected in esophageal squamous cell carcinoma (ESCC), suggesting that this protein may be a potential tumor suppressor. Studies of the mouse counterpart suggested a role of this protein in the transcription regulation that controls germinal differentiation. Multiple alternatively spliced transcript variants encoding the same protein are