MBIP1 Polyclonal Antibody, 50ul miRNA / siRNA Synthesis Mutations in this gene cause

Mutations in this gene cause two forms of inherited human muscle disorders: recessive generalized myotonia congenita (Becker) and dominant myotonia (Thomsen)

also designated Ubiquitin D or Diubiquitin

and insulin-like growth factor 1 (IGF1)

Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product

MBIP1 Polyclonal Antibody, 50ul miRNA / siRNA Synthesis Mutations in this gene causeInhibits the MAP3K12 activity to induce the activation of the JNK SAPK pathway.,subcellular location: Shows a cytoplasmic localization when co expressed with MAP3K12.,tissue specificity: Ubiquitous. High expression seen in the heart and lung.,