CAN13 Polyclonal Antibody, 100ul Pasteur Pipets Mutations in this gene have

Mutations in this gene have been linked to severe spermatogenic failure and infertility in males

There is also evidence for alternative translation initiation from upstream non-AUG (CUG) codons resulting in additional isoforms

Positively regulates vesicle fusion by maintaining the readily releasable pool of secretory vesicles (By similarity)

Cyclins are important regulators of cell cycle transitions through their ability to bind and activate cyclin-dependent protein kinases

CAN13 Polyclonal Antibody, 100ul Pasteur Pipets Mutations in this gene haveThe calpains, calcium activated neutral proteases, are nonlysosomal, intracellular cysteine proteases. The mammalian calpains include ubiquitous, stomach specific, and muscle specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large, catalytic subunits associated with a common small, regulatory subunit. This gene encodes a member of the calpain large subunit family.