O-FucT-2 Polyclonal Antibody, 100ul Lentiviral Packaging Mutations in CHEK2 have been

Mutations in CHEK2 have been linked with Li-Fraumeni syndrome

a variant H2A histone that is enriched on inactivated X chromosomes

is exclusively expressed in testis but it has also been found in a wide variety of cancer tissues and cell lines

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O-FucT-2 Polyclonal Antibody, 100ul Lentiviral Packaging Mutations in CHEK2 have beenFucose is typically found as a terminal modification of branched chain glycoconjugates, but it also exists in direct O linkage to serine or threonine residues within cystine knot motifs in epidermal growth factor (EGF; MIM 131530) like repeats or thrombospondin (THBS; see MIM 188060) type 1 repeats. POFUT2 is an O fucosyltransferase that use THBS type 1 repeats as substrates (Luo et al. 2006 [PubMed 16464857]).