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GFRA2 Polyclonal Antibody, 100ul Cytokines The chondroitin sulfate proteoglycan NG2

SKU: 71812780105

4.3
SEK141.00 SEK180.00

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GFRA2 Polyclonal Antibody, 100ul Cytokines The chondroitin sulfate proteoglycan NG2Glial cell line derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. The protein encoded by this gene is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol(GPI) linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This encoded protein

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Description

The chondroitin sulfate proteoglycan NG2 is a type I membrane protein expressed by subpopulations of glia including oligodendroglial precursor cells and a variety of tumor cells

NCAM1 (neural cell adhesion molecule 1) encodes a cell adhesion protein which is a member of the immunoglobulin superfamily

It also interacts with multiple proteins including calmodulin| CABP1| enkurin| Na(+)-H+ exchange regulatory factor (NHERF )| interferon-induced GTP-binding protein (MX1)| ring finger protein 24 (RNF24)| and SEC14 domain and spectrin repeat-containing protein 1 (SESTD1)

SMG7 encodes protein SMG7 that is essential for nonsense-mediated mRNA decay (NMD)

GFRA2 Polyclonal Antibody, 100ul Cytokines The chondroitin sulfate proteoglycan NG2Glial cell line derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. The protein encoded by this gene is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol(GPI) linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This encoded protein

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