AVR2B Polyclonal Antibody, 20ul Immunology LTE4 and 12-HETE

LTE4 and 12-HETE

Mutations in this gene are associated with gingival fibromatosis 1 and Noonan syndrome type 4

It may also negatively regulate cell proliferation through interaction with the C-terminal region of the adenomatosis polyposis coli tumor suppressor protein

This gene is a member of the G-protein coupled receptor 1 family and encodes a multi-pass membrane protein that localizes to the endoplasmic reticulum

AVR2B Polyclonal Antibody, 20ul Immunology LTE4 and 12-HETEActivins are dimeric growth and differentiation factors which belong to the transforming growth factor beta (TGF beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand binding extracellular domain with cysteine rich