JAK3 Monoclonal Antibody, 50ul Adeno-associated Virus Packaging ay play a role in

ay play a role in T-cell development

The activated ubiquitin ligase complex targets the protein cyclin B1 for degradation

and also Usher syndrome 1J (USH1J)

Three splice variants that encode different isoforms have been identified for this gene

JAK3 Monoclonal Antibody, 50ul Adeno-associated Virus Packaging ay play a role inThe protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease).