Rb Polyclonal Antibody, 100ul[BT-AP07685] Monoclonal Antibody Preparation Alternatively spliced transcript variants encoding

Alternatively spliced transcript variants encoding different isoforms have been described for PDE4C

The BRCA2-Associated Factor 35 (BRAF35) protein forms a complex with BRCA2

specifically require this kinase

There are multiple pseudogenes of this gene dispersed throughout the genome

Rb Polyclonal Antibody, 100ul[BT-AP07685] Monoclonal Antibody Preparation Alternatively spliced transcript variants encodingRB transcriptional corepressor 1 encoded by RB1 is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.