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EHMT2 Polyclonal Antibody, 50ul Cellular Function Assays The encoded preproprotein is proteolytically

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EHMT2 Polyclonal Antibody, 50ul Cellular Function Assays The encoded preproprotein is proteolyticallyThis gene encodes a methyltransferase that methylates lysine residues of histone H3. Methylation of H3 at lysine 9 by this protein results in recruitment of additional epigenetic regulators and repression of transcription. This gene was initially thought to be two different genes, NG36 and G9a, adjacent to each other in the HLA locus. Alternative splicing results in multiple transcript variants.

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Description

The encoded preproprotein is proteolytically processed by furin to generate 515 kDa and 85 kDa subunits that form the mature receptor (PMID: 8546712)

Mutations in ATP7A are associated with Menkes disease

|PTM:The N-terminal processed form GRO-beta(5-73) is produced by proteolytic cleavage after secretion from bone marrow stromal cells

and acts both as a dioxygenase and as a peroxidase

EHMT2 Polyclonal Antibody, 50ul Cellular Function Assays The encoded preproprotein is proteolyticallyThis gene encodes a methyltransferase that methylates lysine residues of histone H3. Methylation of H3 at lysine 9 by this protein results in recruitment of additional epigenetic regulators and repression of transcription. This gene was initially thought to be two different genes, NG36 and G9a, adjacent to each other in the HLA locus. Alternative splicing results in multiple transcript variants.

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