Oct-3/4 Monoclonal Antibody, 50ul[BT-MCA0952] Dry Bath Mutations in CASP10 are associated

Mutations in CASP10 are associated with type IIA autoimmune lymphoproliferative syndrome

The surface expression of these ligands is important for the recognition of stressed cells by the immune system

The protein encoded by PLCG2 (phospholipase C gamma 2) is a transmembrane signaling enzyme that catalyzes the conversion of 1-phosphatidyl-1D-myo-inositol 4

Several transcript variants encoding different isoforms have been found for CFLAR

Oct-3/4 Monoclonal Antibody, 50ul[BT-MCA0952] Dry Bath Mutations in CASP10 are associatedThis gene encodes a transcription factor containing a POU homeodomain that plays a key role in embryonic development and stem cell pluripotency. Aberrant expression of this gene in adult tissues is associated with tumorigenesis. This gene can participate in a translocation with the Ewing's sarcoma gene on chromosome 21, which also leads to tumor formation. Alternative splicing, as well as usage of alternative AUG and non AUG translation initiation