CART Polyclonal Antibody, 50ul Reagent Reservoirs The glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase encoded

The glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase encoded by GNE is a bifunctional enzyme that initiates and regulates the biosynthesis of N-acetylneuraminic acid (NeuAc)

The protein may be involved in transduction of high-temperature heat responses in sensory ganglia

The gamma subunits contain the active site of the enzyme

while the BRISC complex exhibits deubiquitinase activity and is involved in mitotic spindle assembly

CART Polyclonal Antibody, 50ul Reagent Reservoirs The glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase encodedThis gene encodes a preproprotein that is proteolytically processed to generate multiple biologically active peptides. These peptides play a role in appetite, energy balance, maintenance of body weight, reward and addiction, and the stress response. Expression of a similar gene transcript in rodents is upregulated following administration of cocaine and amphetamine. Mutations in this gene are associated with susceptibility to obesity in humans.