AMPK alpha 1(Phospho-Ser485) Rabbit Polyclonal Antibody, 20ul Pathway and Network Analysis The encoded protein contains sequence

The encoded protein contains sequence and structural similarity to members of the neprilysin (M13) family of zinc endopeptidases

and its expression in various tissues suggests a role in both differentiation and maintenance of several cell types

The encoded protein acts as a dominant-negative regulator of transcription which is mediated by the retinoic acid receptor

Yeast Rad18 functions through its interaction with Rad6| which is an ubiquitin-conjugating enzyme required for post-replication repair of damaged DNA

AMPK alpha 1(Phospho-Ser485) Rabbit Polyclonal Antibody, 20ul Pathway and Network Analysis The encoded protein contains sequenceThe protein encoded by this gene belongs to the ser thr protein kinase family. It is the catalytic subunit of the 5' prime AMP activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that