Flt-1 Polyclonal Antibody, 100ul[BT-AP03280] Pathway and Network Analysis The EPH and EPH-related receptors

The EPH and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events

Alternative splicing of this gene results in transcript variants encoding distinct isoforms

Transcripts may include the shared exon spliced to the gene-specific exons

The ratio of soluble to membrane-bound forms increases during acute-phase induction or stress

Flt-1 Polyclonal Antibody, 100ul[BT-AP03280] Pathway and Network Analysis The EPH and EPH-related receptorsFLT1 encodes a member of the vascular endothelial growth factor receptor (VEGFR) family. VEGFR family members are receptor tyrosine kinases (RTKs) which contain an extracellular ligand binding region with seven immunoglobulin (Ig) like domains, a transmembrane segment, and a tyrosine kinase (TK) domain within the cytoplasmic domain. fms related tyrosine kinase 1 binds to VEGFR A, VEGFR B and placental growth factor and plays an important role in