NADL2 Polyclonal Antibody, 100ul Live Cell Imaging Classical cadherins consist of a

Classical cadherins consist of a large extracellular domain which contains DXD and DXNDN repeats responsible for mediating calcium-dependent adhesion

It mediates E3-dependent ubiquitination and proteasomal degradation of target proteins

through the regulatory roles of CDK4 and p53 in cell cycle G1 progression

Mutations in this gene result in sporadic and familial Paget disease of bone

NADL2 Polyclonal Antibody, 100ul Live Cell Imaging Classical cadherins consist of aAlthough related to the peptidase M28 family, it is probably inactive as an hydrolase due to lack of the conserved zinc binding and active sites.,May be catalytically inactive.,miscellaneous: The gene maps to 3q26. 31, a region associated with Cornelia de Lange syndrome. However, PubMed: 15168106 failed to identify specific mutations in a panel of DNA samples from patients with Cornelia de Lange syndrome.,sequence Contaminating sequence at the C