Ku-70 Polyclonal Antibody, 50ul[BT-AP04892] Custom RNA Oligos Alternative splicing results in multiple

Alternative splicing results in multiple variants

Specifically

It also stimulates the mitogen activated protein kinase cascade leading to c-Jun kinase SAPK/JNK1 activation

trafficking of proteins including integrin subunits and epidermal growth factor receptor (EGFR)

Ku-70 Polyclonal Antibody, 50ul[BT-AP04892] Custom RNA Oligos Alternative splicing results in multipleThe p70 p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single stranded DNA dependent ATP dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with