MDM2 Polyclonal Antibody, 100ul[BT-AP05300] Multiplex Immunoassays that is required for anchoring

that is required for anchoring microtubules to subcellular structures

also known as F-actin bundling domain

tissue specificity:Highly expressed in placental JEG-3 cells and very low levels of expression in non-steroidogenic cells

an apoptosis-promoting nuclear RNA-binding protein

MDM2 Polyclonal Antibody, 100ul[BT-AP05300] Multiplex Immunoassays that is required for anchoringMDM2 encodes a nuclear localized E3 ubiquitin ligase. E3 ubiquitin protein ligase Mdm2 can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. MDM2 is itself transcriptionally regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript