IRS-1(Phospho-Ser318) Rabbit Polyclonal Antibody, 50ul Polyclonal Antibodies Cdc45 is a member of

Cdc45 is a member of the highly conserved multiprotein complex including Cdc6/Cdc18

The encoded protein is a phosphohydrolase and may regulate the turnover of diphosphoinositol polyphosphates

Subsequently localizes to the spindle midzone from anaphase and to the midbody from telophase

The protein has no known catalytic function but has been shown to bind and recruit various proteins involved in the regulation of receptor protein tyrosine kinases

IRS-1(Phospho-Ser318) Rabbit Polyclonal Antibody, 50ul Polyclonal Antibodies Cdc45 is a member ofThis gene encodes a protein which is phosphorylated by insulin receptor tyrosine kinase. Mutations in this gene are associated with type II diabetes and susceptibility to insulin resistance.