HAUSP Monoclonal Antibody, 100ul[BT-MCA0663] Pipette Micro Tips The phosphorylated STATs dimerize| associate

The phosphorylated STATs dimerize| associate with ISGF3G/IRF-9 to form a complex termed ISGF3 transcription factor| that enters the nucleus

This gene may be downstream in the WNT1 signaling pathway that is relevant to malignant transformation

This protein has a sequence similarity to yeast Prp8 protein

The inhibitory activity is enhanced by the presence of heparin

HAUSP Monoclonal Antibody, 100ul[BT-MCA0663] Pipette Micro Tips The phosphorylated STATs dimerize| associateThe protein encoded by this gene belongs to the peptidase C19 family, which includes ubiquitinyl hydrolases. This protein deubiquitinates target proteins such as p53 (a tumor suppressor protein) and WASH (essential for endosomal protein recycling), and regulates their activities by counteracting the opposing ubiquitin ligase activity of proteins such as HDM2 and TRIM27, involved in the respective process. Mutations in this gene have been implicated in