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ANGP2 Polyclonal Antibody, 50ul Organelle Studies heme A: farnesyltransferase cytochrome c

SKU: 84134895097

4.5
SEK185.00 SEK233.00

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ANGP2 Polyclonal Antibody, 50ul Organelle Studies heme A: farnesyltransferase cytochrome cThe protein encoded by this gene is an antagonist of angiopoietin 1 (ANGPT1) and endothelial TEK tyrosine kinase (TIE 2, TEK). The encoded protein disrupts the vascular remodeling ability of ANGPT1 and may induce endothelial cell apoptosis. Three transcript variants encoding three different isoforms have been found for this gene.

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Description

heme A: farnesyltransferase cytochrome c oxidase assembly factor is predicted to contain 7-9 transmembrane domains localized in the mitochondrial inner membrane

Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH

Interacts with CUL4B and DDB1

A related protein in mouse is responsible for the activation of lymphocyte-specific protein-tyrosine kinase and functions in downstream signaling

ANGP2 Polyclonal Antibody, 50ul Organelle Studies heme A: farnesyltransferase cytochrome cThe protein encoded by this gene is an antagonist of angiopoietin 1 (ANGPT1) and endothelial TEK tyrosine kinase (TIE 2, TEK). The encoded protein disrupts the vascular remodeling ability of ANGPT1 and may induce endothelial cell apoptosis. Three transcript variants encoding three different isoforms have been found for this gene.

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