APLP-1 Polyclonal Antibody, 20ul Cell Culture & Maintenance Take on the challenge of

Take on the challenge of scientific discovery today

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X-linked distal spinal muscular atrophy

ATXN7L3 localizes to nucleus and contains one SCA7 domain and one SGF11-type zinc finger

APLP-1 Polyclonal Antibody, 20ul Cell Culture & Maintenance Take on the challenge ofAPLP1 encodes a member of the highly conserved amyloid precursor protein gene family. The amyloid like protein 1 is a membrane associated glycoprotein that is cleaved by secretases in a manner similar to amyloid beta A4 precursor protein cleavage. This cleavage liberates an intracellular cytoplasmic fragment that may act as a transcriptional activator. The encoded protein may also play a role in synaptic maturation during cortical development.